Tobacco smoking

Tobacco smoking is the practice where tobacco is burned and the resulting smoke (consisting of particle and gaseous phases) is inhaled. The practice may have begun as early as 5000–3000 BC.[1] Tobacco was introduced to Eurasia in the late 16th century where it followed common trade routes. The practice encountered criticism from its first import into the Western world onwards, but embedded itself in certain strata of a number of societies before becoming widespread upon the introduction of automated cigarette-rolling apparatus.[2][3]

German scientists identified a link between smoking and lung cancer in the late 1920s, leading to the first anti-smoking campaign in modern history, albeit one truncated by the collapse of the Third Reich at the end of the Second World War.[4] In 1950, British researchers demonstrated a clear relationship between smoking and cancer.[5] Scientific evidence continued to mount in the 1980s, which prompted political action against the practice. Rates of consumption since 1965 in the developed world have either peaked or declined.[6] However, they continue to climb in the developing world.[7]

Smoking is the most common method of consuming tobacco, and tobacco is the most common substance smoked. The agricultural product is often mixed with additives[8] and then pyrolyzed. The resulting smoke is then inhaled and the active substances absorbed through the alveoli in the lungs.[9] The active substances trigger chemical reactions in nerve endings, which heighten heart rate, alertness,[10] and reaction time.[11] Dopamine and endorphins are released, which are often associated with pleasure.[12] As of 2000, smoking is practiced by approximately 1.22 billion people. In most communities men are more likely to smoke than are women,[13] though the gender gap tends to be less pronounced in lower age groups.[14][15]

Many smokers begin during adolescence or early adulthood. During the early stages, a combination of perceived pleasure acting as positive reinforcement and desire to respond to social peer pressure may offset the unpleasant symptoms of initial use, which typically include nausea and interrupted sleep patterns. After an individual has smoked for some years, the avoidance of withdrawal symptoms and negative reinforcement become the key motivations to continue.

Contents

History

Early years

Smoking's history dates back to as early as 5000–3000 BC when the agricultural product began to be cultivated in South America; consumption later evolved into burning the plant substance either by accident or with intent of exploring other means of consumption.Many ancient civilisations — such as the Babylonians, the Indians, and the Chinese — burnt incense during religious rituals. . Smoking in the Americas probably had its origins in the incense-burning ceremonies of shamans but was later adopted for pleasure or as a social tool

Eastern North American tribes would carry large amounts of tobacco in pouches as a readily accepted trade item and would often smoke it in pipes, either in sacred ceremonies or to seal bargains.

Apart from smoking, tobacco had a number of uses as medicine. As a pain killer it was used for earache and toothache and occasionally as a poultice. Smoking was said by the desert Indians to be a cure for colds, especially if the tobacco was mixed with the leaves of the small Desert Sage, Salvia Dorrii, or the root of Indian Balsam or Cough Root, Leptotaenia multifida, the addition of which was thought to be particularly good for asthma and tuberculosis

Popularisation

In 1612, six years after the settlement of Jamestown, John Rolfe was credited as the first settler to successfully raise tobacco as a cash crop. The demand quickly grew as tobacco, referred to as "brown gold", reviving the Virginia joint stock company from its failed gold expeditions.[16] In order to meet demands from the Old World, tobacco was grown in succession, quickly depleting the soil. This became a motivator to settle west into the unknown continent, and likewise an expansion of tobacco production.[17] Indentured servitude became the primary labor force up until Bacon's Rebellion, from which the focus turned to slavery.[18] This trend abated following the American revolution as slavery became regarded as unprofitable. However, the practice was revived in 1794 with the invention of the cotton gin[19].

Frenchman Jean Nicot (from whose name the word nicotine is derived) introduced tobacco to France in 1560, and tobacco then spread to England. The first report of a smoking Englishman is of a sailor in Bristol in 1556, seen "emitting smoke from his nostrils"[2]. Like tea, coffee and opium, tobacco was just one of many intoxicants that was originally used as a form of medicine.[20] Tobacco was introduced around 1600 by French merchants in what today is modern-day Gambia and Senegal. At the same time caravans from Morocco brought tobacco to the areas around Timbuktu and the Portuguese brought the commodity (and the plant) to southern Africa, establishing the popularity of tobacco throughout all of Africa by the 1650s.

Soon after its introduction to the Old World, tobacco came under frequent criticism from state and religious leaders. Murad IV, sultan of the Ottoman Empire 1623-40 was among the first to attempt a smoking ban by claiming it was a threat to public moral and health. The Chinese emperor Chongzhen issued an edict banning smoking two years before his death and the overthrow of the Ming dynasty. Later, the Manchu of the Qing dynasty, who were originally a tribe of nomadic horse warriors, would proclaim smoking "a more heinous crime than that even of neglecting archery". In Edo period Japan, some of the earliest tobacco plantations were scorned by the shogunate as being a threat to the military economy by letting valuable farmland go to waste for the use of a recreational drug instead of being used to plant food crops[21].

Religious leaders have often been prominent among those who considered smoking immoral or outright blasphemous. In 1634 the Patriarch of Moscow forbade the sale of tobacco, and sentenced men and women who flouted the ban to have their nostrils slit and their backs flayed. The Western church leader Urban VII likewise condemned smoking on holy places in a papal bull of 1624. Despite some concerted efforts, restrictions and bans were largely ignored. When James I of England, a staunch anti-smoker and the author of a A Counterblaste to Tobacco, tried to curb the new trend by enforcing a 4000% tax increase on tobacco in 1604 it was unsuccessful, as suggested by the presence of around 7,000 tobacco outlets in London by the early 17th century. From this point on for some centuries, several administrations with drew from efforts at discouragement and instead turned tobacco trade and cultivation into sometimes lucrative government monopolies[22][23].

By the mid-17th century most major civilisations had been introduced to tobacco smoking and in many cases had already assimilated it into the native culture, despite some continued attempts upon the parts of rulers to eliminate the practice with penalties or fines. Tobacco, both product and plant, followed the major trade routes to major ports and markets, and then on into the hinterlands. The English language term smoking appears to have entered currency in the late 18th century, before which less abbreviated descriptions of the practice such as drinking smoke were also in use[2].

Growth in the US remained stable until the American Civil War in 1860s, when the primary agricultural workforce shifted from slavery to share cropping. This, along with a change in demand, accompanied the industrialisation of cigarette production as craftsman James Bonsack created a machine in 1881 to partially automate their manufacture[24].

Social attitudes and public health

In Germany, anti-smoking groups, often associated with anti-liquor groups,[25] first published advocacy against the consumption of tobacco in the journal Der Tabakgegner (The Tobacco Opponent) in 1912 and 1932. In 1929, Fritz Lickint of Dresden, Germany, published a paper containing formal statistical evidence of a lung cancer–tobacco link. During the Great depression Adolf Hitler condemned his earlier smoking habit as a waste of money,[26] and later with stronger assertions. This movement was further strengthened with Nazi reproductive policy as women who smoked were viewed as unsuitable to be wives and mothers in a German family.[27]

The anti-tobacco movement in Nazi Germany did not reach across enemy lines during the Second World War, as anti-smoking groups quickly lost popular support. By the end of the Second World War, American cigarette manufacturers quickly reentered the German black market. Illegal smuggling of tobacco became prevalent,[28] and leaders of the Nazi anti-smoking campaign were silenced.[29] As part of the Marshall Plan, the United States shipped free tobacco to Germany; with 24,000 tons in 1948 and 69,000 tons in 1949.[28] Per capita yearly cigarette consumption in post-war Germany steadily rose from 460 in 1950 to 1,523 in 1963.[4] By the end of the 20th century, anti-smoking campaigns in Germany were unable to exceed the effectiveness of the Nazi-era climax in the years 1939–41 and German tobacco health research was described by Robert N. Proctor as "muted".[4]

Richard Doll in 1950 published research in the British Medical Journal showing a close link between smoking and lung cancer.[30] Four years later, in 1954 the British Doctors Study, a study of some 40 thousand doctors over 20 years, confirmed the suggestion, based on which the government issued advice that smoking and lung cancer rates were related.[5] In 1964 the United States Surgeon General's Report on Smoking and Health likewise began suggesting the relationship between smoking and cancer.

As scientific evidence mounted in the 1980s, tobacco companies claimed contributory negligence as the adverse health effects were previously unknown or lacked substantial credibility. Health authorities sided with these claims up until 1998, from which they reversed their position. The Tobacco Master Settlement Agreement, originally between the four largest US tobacco companies and the Attorneys General of 46 states, restricted certain types of tobacco advertisement and required payments for health compensation; which later amounted to the largest civil settlement in United States history.[31]

From 1965 to 2006, rates of smoking in the United States declined from 42% to 20.8%.[6] The majority of those who quit were professional, affluent men. Although the per-capita number of smokers decreased, the average number of cigarettes consumed per person per day increased from 22 in 1954 to 30 in 1978. This paradoxical event suggests that those who quit smoked less, while those who continued to smoke moved to smoke more light cigarettes.[32] The trend has been paralleled by many industrialized nations as rates have either leveled-off or declined. In the developing world, however, tobacco consumption continues to rise at 3.4% in 2002.[7] In Africa, smoking is in most areas considered to be modern, and many of the strong adverse opinions that prevail in the West receive much less attention.[33] Today Russia leads as the top consumer of tobacco followed by Indonesia, Laos, Ukraine, Belarus, Greece, Jordan, and China.[34]

Consumption

Methods

Tobacco is an agricultural product processed from the fresh leaves of plants in the genus Nicotiana. The genus contains a number of species, however, Nicotiana tabacum is the most commonly grown. Nicotiana rustica follows as second containing higher concentrations of nicotine. These leaves are harvested and cured to allow for the slow oxidation and degradation of carotenoids in tobacco leaf. This produces certain compounds in the tobacco leaves which can be attributed to sweet hay, tea, rose oil, or fruity aromatic flavors. Before packaging, the tobacco is often combined with other additives in order to: enhance the addictive potency, shift the products pH, or improve the effects of smoke by making it more palatable. In the United States these additives are regulated to 599 substances.[8] The product is then processed, packaged, and shipped to consumer markets. Means of consumption has greatly expanded in scope as new methods of delivering the active substances with fewer by-products have encompassed or are beginning to encompass:

Tobacco field in Intercourse, Pennsylvania.
Basma leaves curing in the sun at Pomak village of Xanthi, Thrace, Greece.
Processed tobacco pressed into long strips for shipping.
Beedi
Beedis are thin South Asian cigarettes filled with tobacco flake and wrapped in a tendu leaf tied with a string at one end. They produce higher levels of carbon monoxide, nicotine, and tar than cigarettes typical in the United States.[35][36]
Cigars
Cigars are tightly rolled bundles of dried and fermented tobacco which are ignited so that smoke may be drawn into the smoker's mouth. They are generally not inhaled because the high alkalinity of the smoke, which can quickly become irritating to the trachea and lungs. The prevalence of cigar smoking varies depending on location, historical period, and population surveyed, and prevalence estimates vary somewhat depending on the survey method. The United States is the top consuming country by far, followed by Germany and the United Kingdom; the US and Western Europe account for about 75% of cigar sales worldwide.[37] As of 2005 it is estimated that 4.3% of men and 0.3% of women smoke cigars in USA.[38]
Cigarettes
Cigarettes, French for "small cigar", are a product consumed through smoking and manufactured out of cured and finely cut tobacco leaves and reconstituted tobacco, often combined with other additives, which are then rolled or stuffed into a paper-wrapped cylinder.[8] Cigarettes are ignited and inhaled, usually through a cellulose acetate filter, into the mouth and lungs.
Electronic cigarette
Electronic cigarettes are an alternative to tobacco smoking, although no tobacco is consumed. It is a battery-powered device that provides inhaled doses of nicotine by delivering a vaporized propylene glycol/nicotine solution. Many legislation and public health investigations are currently pending in many countries due to its relatively recent emergence. Most electronic cigarettes are designed to resemble actual tobacco smoking implements, such as cigarettes, cigars, or pipes, but many take the form of ballpoint pens or screwdrivers since those designs are more practical to house the mechanisms involved. Most are also reusable, with replaceable and refillable parts, but some models are disposable.
Hookah
Hookah are a single or multi-stemmed (often glass-based) water pipe for smoking. Originally from India. The hookah was a symbol of pride and honour for the landlords, kings and other such high class people. Now,the hookah has gained immense popularity, especially in the Middle East. A hookah operates by water filtration and indirect heat. It can be used for smoking herbal fruits, tobacco, or cannabis.
Kretek
Kretek are cigarettes made with a complex blend of tobacco, cloves and a flavoring "sauce". It was first introduced in the 1880s in Kudus, Java, to deliver the medicinal eugenol of cloves to the lungs. The quality and variety of tobacco play an important role in kretek production, from which kretek can contain more than 30 types of tobacco. Minced dried clove buds weighing about 1/3 of the tobacco blend are added to add flavoring. In 2004 the United States prohibited cigarettes from having a "characterizing flavor" of certain ingredients other than tobacco and menthol, thereby removing kretek from being classified as cigarettes.[39]
Passive smoking
Passive smoking is the usually involuntary consumption of smoked tobacco. Second-hand smoke (SHS) is the consumption where the burning end is present, environmental tobacco smoke (ETS) or third-hand smoke is the consumption of the smoke that remains after the burning end has been extinguished. Because of its perceived negative implications, this form of consumption has played a central role in the regulation of tobacco products.
Pipe smoking
Pipe smoking typically consists of a small chamber (the bowl) for the combustion of the tobacco to be smoked and a thin stem (shank) that ends in a mouthpiece (the bit). Shredded pieces of tobacco are placed into the chamber and ignited. Tobaccos for smoking in pipes are often carefully treated and blended to achieve flavour nuances not available in other tobacco products.
Roll-Your-Own
Roll-Your-Own or hand-rolled cigarettes, often called 'rollies', are very popular particularly in European countries. These are prepared from loose tobacco, cigarette papers, and filters all bought separately. They are usually much cheaper than ready-made cigarettes.
Vaporizer
A vaporizer is a device used to sublimate the active ingredients of plant material. Rather than burning the herb, which produces potentially irritating, toxic, or carcinogenic by-products; a vaporizer heats the material in a partial vacuum so that the active compounds contained in the plant boil off into a vapor. Medical administration of a smoke substance often prefer this method as to directly pyrolyzing the plant material.

Physiology

The active substances in tobacco, especially cigarettes, are administered by burning the leaves and inhaling the vaporised gas that results. This quickly and effectively delivers substances into the bloodstream by absorption through the alveoli in the lungs. The lungs contain some 300 million alveoli, which amounts to a surface area of over 70 m2 (about the size of a tennis court). This method is not completely efficient as not all of the smoke will be inhaled, and some amount of the active substances will be lost in the process of combustion, pyrolysis.[9] Pipe and Cigar smoke are not inhaled because of its high alkalinity, which are irritating to the trachea and lungs. However, because of its higher alkalinity (pH 8.5) compared to cigarette smoke (pH 5.3), non-ionised nicotine is more readily absorbed through the mucous membranes in the mouth.[40] Nicotine absorption from cigar and pipe, however, is much less than that from cigarette smoke.[41]

The inhaled substances trigger chemical reactions in nerve endings. The cholinergic receptors are often triggered by the naturally occurring neurotransmitter acetylcholine. Acetylcholine and Nicotine express chemical similarities, which allows Nicotine to trigger the receptor as well.[42] These nicotinic acetylcholine receptors takes are located in the central nervous system and at the nerve-muscle junction of skeletal muscles; whose activity increases heart rate, alertness,[10] and faster reaction times.[11] Nicotine acetylcholine stimulation is not directly addictive. However, since dopamine-releasing neurons are abundant on nicotine receptors, dopamine is released.[43] This release of dopamine, which is associated with pleasure, is reinforcing and may also increase working memory.[12][44] Nicotine and cocaine activate similar patterns of neurons, which supports the idea that common substrates among these drugs.[45]

When tobacco is smoked, most of the nicotine is pyrolyzed. However, a dose sufficient to cause mild somatic dependency and mild to strong psychological dependency remains. There is also a formation of harmane (a MAO inhibitor) from the acetaldehyde in tobacco smoke. This may play a role in nicotine addiction, by facilitating a dopamine release in the nucleus accumbens as a response to nicotine stimuli.[46] Using rat studies, withdrawal after repeated exposure to nicotine results in less responsive nucleus accumbens cells, which produce dopamine responsible for reinforcement.[47]

Demographics

Percentage of females smoking any tobacco product
Percentage of males smoking any tobacco product. Note that there is a difference between the scales used for females and the scales used for males.[34]

As of 2000, smoking was practised by around 1.22 billion people. At current rates of 'smoker replacement' and market growth, this may reach around 1.9 billion in 2025.[13]

Smoking may be up to five times more prevalent amongst men than women in some communities,[13] although the gender gap usually declines with younger age.[14][15] In some developed countries smoking rates for men have peaked and begun to decline, while for women they continue to climb.[48]

As of 2002, about twenty percent of young teenagers (13–15) smoked worldwide. From which 80,000 to 100,000 children begin smoking every day, roughly half of whom live in Asia. Half of those who begin smoking in adolescent years are projected to go on to smoke for 15 to 20 years.[7]

The World Health Organization (WHO) states that "Much of the disease burden and premature mortality attributable to tobacco use disproportionately affect the poor". Of the 1.22 billion smokers, 1 billion of them live in developing or transitional economies. Rates of smoking have leveled off or declined in the developed world.[49] In the developing world, however, tobacco consumption is rising by 3.4% per year as of 2002.[7]

The WHO in 2004 projected 58.8 million deaths to occur globally,[50] from which 5.4 million are tobacco-attributed,[51] and 4.9 million as of 2007.[52] As of 2002, 70% of the deaths are in developing countries.[52]

Psychology

Takeup

Most smokers begin during adolescence or early adulthood. Smoking has elements of risk-taking and rebellion, which often appeal to young people. The presence of peers that smoke and media featuring high-status models smoking may also encourage smoking. Because teenagers are influenced more by their peers than by adults, attempts by parents, schools, and health professionals at preventing people from trying cigarettes are unsuccessful.[54][55]

Children of smoking parents are more likely to smoke than children with non-smoking parents. One study found that parental smoking cessation was associated with less adolescent smoking, except when the other parent currently smoked.[56] A current study tested the relation of adolescent smoking to rules regulating where adults are allowed to smoke in the home. Results showed that restrictive home smoking policies were associated with lower likelihood of trying smoking for both middle and high school students.[57]

Behavioural research generally indicates that teenagers begin their smoking habits due to peer pressure, and cultural influence portrayed by friends. However, one study found that direct pressure to smoke cigarettes played a less significant part in adolescent smoking, with adolescents also reporting low levels of both normative and direct pressure to smoke cigarettes.[58] A similar study suggested that individuals may play a more active role in starting to smoke than has previously been thought and that social processes other than peer pressure also need to be taken into account.[59] Another study's results indicated that peer pressure was significantly associated with smoking behaviour across all age and gender cohorts, but that intrapersonal factors were significantly more important to the smoking behaviour of 12–13 year-old girls than same-age boys. Within the 14–15 year-old age group, one peer pressure variable emerged as a significantly more important predictor of girls' than boys' smoking.[60] It is debated whether peer pressure or self-selection is a greater cause of adolescent smoking.

Psychologists such as Hans Eysenck have developed a personality profile for the typical smoker. Extraversion is the trait that is most associated with smoking, and smokers tend to be sociable, impulsive, risk taking, and excitement seeking individuals.[61] Although personality and social factors may make people likely to smoke, the actual habit is a function of operant conditioning. During the early stages, smoking provides pleasurable sensations (because of its action on the dopamine system) and thus serves as a source of positive reinforcement.

Persistence

The reasons given by some smokers for this activity have been categorised as addictive smoking, pleasure from smoking, tension reduction/relaxation, social smoking, stimulation, habit/automatism, and handling. There are gender differences in how much each of these reasons contribute, with females more likely than males to cite tension reduction/relaxation, stimulation and social smoking.[62]

Some smokers argue that the depressant effect of smoking allows them to calm their nerves, often allowing for increased concentration. However, according to the Imperial College London, "Nicotine seems to provide both a stimulant and a depressant effect, and it is likely that the effect it has at any time is determined by the mood of the user, the environment and the circumstances of use. Studies have suggested that low doses have a depressant effect, while higher doses have stimulant effect."[63]

Patterns

A number of studies have established that cigarette sales and smoking follow distinct time-related patterns. For example, cigarette sales in the United States of America have been shown to follow a strongly seasonal pattern, with the high months being the months of summer, and the low months being the winter months.[64]

Similarly, smoking has been shown to follow distinct circadian patterns during the waking day—with the high point usually occurring shortly after waking in the morning, and shortly before going to sleep at night.[65]

Impact

Economic

In countries where there is a publicly-funded healthcare system, society covers the cost of medical care for smokers who become ill through in the form of increased taxes. Two broad debating positions exist on this front, the "pro-smoking" argument suggesting that heavy smokers generally don't live long enough to develop the costly and chronic illnesses which affect the elderly, reducing society's healthcare burden, and the "anti-smoking" argument suggests that the healthcare burden is increased because smokers get chronic illnesses younger and at a higher rate than the general population. Data on both positions has been contested. The Centers for Disease Control and Prevention published research in 2002 claiming that the cost of each pack of cigarettes sold in the United States was more than $7 in medical care and lost productivity.[66] The cost may be higher, with another study putting it as high as $41 per pack, most of which however is on the individual and his/her family.[67] This is how one author of that study puts it when he explains the very low cost for others: "The reason the number is low is that for private pensions, Social Security, and Medicare — the biggest factors in calculating costs to society — smoking actually saves money. Smokers die at a younger age and don't draw on the funds they've paid into those systems."[67]

By contrast, some non-scientific studies, including one conducted by Philip Morris in the Czech Republic[68] and another by the Cato Institute,[69] support the opposite position. Philip Morris has explicitly apologised for the former study, saying: "The funding and public release of this study which, among other things, detailed purported cost savings to the Czech Republic due to premature deaths of smokers, exhibited terrible judgment as well as a complete and unacceptable disregard of basic human values. For one of our tobacco companies to commission this study was not just a terrible mistake, it was wrong. All of us at Philip Morris, no matter where we work, are extremely sorry for this. No one benefits from the very real, serious and significant diseases caused by smoking."[68]

Between 1970 an 1995, per-capita cigarette consumption in poorer developing countries increased by 67 percent, while it dropped by 10 percent in the richer developed world. Eighty percent of smokers now live in less developed countries. By 2030, the World Health Organization (WHO) forecasts that 10 million people a year will die of smoking-related illness, making it the single biggest cause of death worldwide, with the largest increase to be among women. WHO forecasts the 21st century's death rate from smoking to be ten times the 20th century's rate. ("Washingtonian" magazine, December 2007).

Health

Tobacco use leads most commonly to diseases affecting the heart and lungs, with smoking being a major risk factor for heart attacks, strokes, chronic obstructive pulmonary disease (COPD), emphysema, and cancer (particularly lung cancer, cancers of the larynx and mouth, and pancreatic cancer). Cigarette smoking increases the risk of Crohn's disease as well as the severity of the course of the disease.[71] It is also the number one cause of bladder cancer.

The World Health Organization estimate that tobacco caused 5.4 million deaths in 2004[72] and 100 million deaths over the course of the 20th century.[73] Similarly, the United States Centers for Disease Control and Prevention describes tobacco use as "the single most important preventable risk to human health in developed countries and an important cause of premature death worldwide."[74]

Lung cancer occurs at non-smokers in 3.4 cases per 100 000 population. At people smoking 0.5 packs of cigarettes a day this figure rises to 51.4 per 100 000, 1-2 packs - up to 143.9 per 100 000 and if the intensity of smoking is over 2 packs a day - up to 217.3 per 100,000 population.

Rates of smoking have leveled off or declined in the developed world. Smoking rates in the United States have dropped by half from 1965 to 2006 falling from 42% to 20.8% in adults.[75] In the developing world, tobacco consumption is rising by 3.4% per year.[76]

Passive smoking presents a very real health risk. Six hundred thousand deaths were attributable to second-hand smoke in 2004.[77]

Social

Famous smokers of the past used cigarettes or pipes as part of their image, such as Jean Paul Sartre's Gauloises-brand cigarettes; Albert Einstein's, Douglas MacArthur's, Bertrand Russell's, and Bing Crosby's pipes; or the news broadcaster Edward R. Murrow's cigarette. Writers in particular seem to be known for smoking, for example, Cornell Professor Richard Klein's book Cigarettes are Sublime for the analysis, by this professor of French literature, of the role smoking plays in 19th and 20th century letters. The popular author Kurt Vonnegut addressed his addiction to cigarettes within his novels. British Prime Minister Harold Wilson was well known for smoking a pipe in public as was Winston Churchill for his cigars. Sherlock Holmes, the fictional detective created by Sir Arthur Conan Doyle smoked a pipe, cigarettes, and cigars. The DC Vertigo comic book character, John Constantine, created by Alan Moore, is synonymous with smoking, so much so that the first storyline by Preacher creator, Garth Ennis, centered around John Constantine contracting lung cancer. Professional wrestler James Fullington, while in character as "The Sandman", is a chronic smoker in order to appear "tough".

The problem of smoking at home is particularly difficult for women in many cultures especially Arab cultures where it may not be acceptable for a woman to ask her husband not to smoke at home or in the presence of her children. Studies has shown that pollution levels in door places are higher than levels found on busy roadways, in closed motor garages, and during fire storms. Furthermore, smoke can spread from one room to another, even if doors to the smoking area are closed[78].

The ceremonial smoking of tobacco, and praying with a sacred pipe, is a prominent part of the religious ceremonies of a number of Native American Nations. Sema, the Anishinaabe word for tobacco, is grown for ceremonial use and considered the ultimate sacred plant since its smoke was believed to carry prayers to the heavens. In most major religions, however, tobacco smoking is not specifically prohibited, although it may be discouraged as an immoral habit. Before the health risks of smoking were identified through controlled study, smoking was considered an immoral habit by certain Christian preachers and social reformers. The founder of the Latter Day Saint movement, Joseph Smith, Jr, recorded that on February 27, 1833, he received a revelation which discouraged tobacco use. This "Word of Wisdom" was later accepted as a commandment, and faithful Latter-day Saints abstain completely from tobacco.[79] Jehovah's Witnesses base their stand against smoking on the Bible's command to "clean ourselves of every defilement of flesh" (2 Corinthians 7:1). The Jewish Rabbi Yisrael Meir Kagan (1838–1933) was one of the first Jewish authorities to speak out on smoking. In the Bahá'í Faith, smoking tobacco is discouraged though not forbidden[80].

Public policy

On February 27, 2005 the WHO Framework Convention on Tobacco Control, took effect. The FCTC is the world's first public health treaty. Countries that sign on as parties agree to a set of common goals, minimum standards for tobacco control policy, and to cooperate in dealing with cross-border challenges such as cigarette smuggling. Currently the WHO declares that 4 billion people will be covered by the treaty, which includes 168 signatories.[81] Among other steps, signatories are to put together legislation that will eliminate secondhand smoke in indoor workplaces, public transport, indoor public places and, as appropriate, other public places.

Taxation

Many governments have introduced excise taxes on cigarettes in order to reduce the consumption of cigarettes.

In 2002, the Centers for Disease Control and Prevention said that each pack of cigarettes sold in the United States costs the nation more than $7 in medical care and lost productivity,[66] around $3400 per year per smoker. Another study by a team of health economists finds the combined price paid by their families and society is about $41 per pack of cigarettes.[82]

Substantial scientific evidence shows that higher cigarette prices result in lower overall cigarette consumption. Most studies indicate that a 10% increase in price will reduce overall cigarette consumption by 3% to 5%. Youth, minorities, and low-income smokers are two to three times more likely to quit or smoke less than other smokers in response to price increases.[83][84] Smoking is often cited as an example of an inelastic good, however, i.e. a large rise in price will only result in a small decrease in consumption.

Many nations have implemented some form of tobacco taxation. As of 1997, Denmark had the highest cigarette tax burden of $4.02 per pack. Taiwan only had a tax burden of $0.62 per pack. The federal government of the United States charges $1.01 per pack.[85]

Cigarette taxes vary widely from state to state in the United States. For example, Missouri has a cigarette tax of only 17 cents per pack, the nation's lowest, while New York has the highest cigarette tax in the U.S.: $4.35 per pack. In Alabama, Illinois, Missouri, New York City, Tennessee, and Virginia, counties and cities may impose an additional limited tax on the price of cigarettes.[86] Sales taxes are also levied on tobacco products in most jurisdictions.

In the United Kingdom, a packet of 20 cigarettes typically costs between £5.22 and £8.00 depending on the brand purchased and where the purchase was made.[87] The UK has a significant black market for tobacco, and it has been estimated by the tobacco industry that 27% of cigarette and 68% of handrolling tobacco consumption is non-UK duty paid (NUKDP).[88]

In Australia total taxes account for 62.5% of the final price of a packet of cigarettes (2011 figures). These taxes include federal excise or customs duty, and the more recently introduced Goods and Services Tax (GST).[89]

Restrictions

In June 1967, the US Federal Communications Commission ruled that programmes broadcast on a television station which discussed smoking and health were insufficient to offset the effects of paid advertisements that were broadcast for five to ten minutes each day. In April 1970, the US Congress passed the Public Health Cigarette Smoking Act banning the advertising of cigarettes on television and radio starting on January 2, 1971.[90]

The Tobacco Advertising Prohibition Act 1992 expressly prohibited almost all forms of Tobacco advertising in Australia, including the sponsorship of sporting or other cultural events by cigarette brands.

All tobacco advertising and sponsorship on television has been banned within the European Union since 1991 under the Television Without Frontiers Directive (1989)[91]. This ban was extended by the Tobacco Advertising Directive, which took effect in July 2005 to cover other forms of media such as the internet, print media, and radio. The directive does not include advertising in cinemas and on billboards or using merchandising – or tobacco sponsorship of cultural and sporting events which are purely local, with participants coming from only one Member State[92] as these fall outside the jurisdiction of the European Commission. However, most member states have transposed the directive with national laws that are wider in scope than the directive and cover local advertising. A 2008 European Commission report concluded that the directive had been successfully transposed into national law in all EU member states, and that these laws were well implemented.[93]

Some countries also impose legal requirements on the packaging of tobacco products. For example in the countries of the European Union, Turkey, Australia[94] and South Africa, cigarette packs must be prominently labeled with the health risks associated with smoking.[95] Canada, Australia, Thailand, Iceland and Brazil have also imposed labels upon cigarette packs warning smokers of the effects, and they include graphic images of the potential health effects of smoking. Cards are also inserted into cigarette packs in Canada. There are sixteen of them, and only one comes in a pack. They explain different methods of quitting smoking. Also, in the United Kingdom, there have been a number of graphic NHS advertisements, one showing a cigarette filled with fatty deposits, as if the cigarette is symbolising the artery of a smoker.

Many countries have a smoking age, In many countries, including the United States, most European Union member states, New Zealand, Canada, South Africa, Israel, India, Brazil, Chile, Costa Rica and Australia, it is illegal to sell tobacco products to minors and in the Netherlands, Austria, Belgium, Denmark and South Africa it is illegal to sell tobacco products to people under the age of 16. On September 1, 2007 the minimum age to buy tobacco products in Germany rose from 16 to 18, as well as in the United Kingdom where on October 1, 2007 it rose from 16 to 18.[96] Underlying such laws is the belief that people should make an informed decision regarding the risks of tobacco use. These laws have a lax enforcement in some nations and states. In China, Turkey, and many other countries usually a child will have little problem buying tobacco products, because they are often told to go to the store to buy tobacco for their parents.

Several countries such as Ireland, Latvia, Estonia, the Netherlands, France, Finland, Norway, Canada, Australia, Sweden, Portugal, Singapore, Italy, Indonesia, India, Lithuania, Chile, Spain, Iceland, United Kingdom, Slovenia, Turkey and Malta have legislated against smoking in public places, often including bars and restaurants. Restaurateurs have been permitted in some jurisdictions to build designated smoking areas (or to prohibit smoking). In the United States, many states prohibit smoking in restaurants, and some also prohibit smoking in bars. In provinces of Canada, smoking is illegal in indoor workplaces and public places, including bars and restaurants. As of March 31, 2008 Canada has introduced a smoke-free law ban in all public places, as well as within 10 metres of an entrance to any public place. In Australia, smoke-free laws vary from state to state. Currently, Queensland has completely smoke-free indoor public places (including workplaces, bars, pubs and eateries) as well as patrolled beaches and some outdoor public areas. There are, however, exceptions for designated smoking areas. In Victoria, smoking is restricted in railway stations, bus stops and tram stops as these are public locations where second-hand smoke can affect non-smokers waiting for public transport, and since July 1, 2007 is now extended to all indoor public places. In New Zealand and Brazil, smoking is restricted in enclosed public places including bars, restaurants and pubs. Hong Kong restricted smoking on January 1, 2007 in the workplace, public spaces such as restaurants, karaoke rooms, buildings, and public parks (bars which do not admit minors were exempt until 2009). In Romania smoking is illegal in trains, metro stations, public institutions (except where designated, usually outside) and public transport.

Ignition safety

An indirect public health problem posed by cigarettes is that of accidental fires, usually linked with consumption of alcohol. Numerous cigarette designs have been proposed, some by tobacco companies themselves, which would extinguish a cigarette left unattended for more than a minute or two, thereby reducing the risk of fire. Among American tobacco companies, some have resisted this idea, while others have embraced it. RJ Reynolds was a leader in making prototypes of these cigarettes in 1983[97] and will make all of their U.S. market cigarettes to be fire-safe by 2010.[98] Phillip Morris is not in active support of it.[99] Lorillard, the US's third largest tobacco company, seems to be ambivalent.[99]

Gateway drug theory

The relationship between tobacco and other drug use has been well-established, however the nature of this association remains unclear. The two main theories are the phenotypic causation (gateway) model and the correlated liabilities model. The causation model argues that smoking is a primary influence on future drug use,[100] while the correlated liabilities model argues that smoking and other drug use are predicated on genetic or environmental factors.[101]

Cessation

Smoking cessation, referred to as "quitting" is the action leading towards abstinence of tobacco smoking. There are a number of methods such as cold turkey, nicotine replacement therapy, antidepressants, hypnosis, self-help, and support groups.

See also

References

  1. ^ Cite error: Invalid <ref> tag; no text was provided for refs named Gateley2004; see Help:Cite errors/Cite error references no text
  2. ^ a b c Lloyd, John; Mitchinson, John (2008-07-25). The Book of General Ignorance. Harmony Books. ISBN 0307394913 
  3. ^ West, Robert and Shiffman, Saul (2007). Fast Facts: Smoking Cessation. Health Press Ltd.. p. 28. ISBN 978-1-903734-98-8. 
  4. ^ a b c Proctor 2000, p. 228
  5. ^ a b Doll, R.; Hill, B. (Jun 2004). "The mortality of doctors in relation to their smoking habits: a preliminary report: (Reprinted from Br Med J 1954:ii;1451-5)". BMJ (Clinical research ed.) 328 (7455): 1529–1533; discussion 1533. doi:10.1136/bmj.328.7455.1529. ISSN 0959-8138. PMC 437141. PMID 15217868. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=437141.  edit
  6. ^ a b VJ Rock, MPH, A Malarcher, PhD, JW Kahende, PhD, K Asman, MSPH, C Husten, MD, R Caraballo, PhD (2007-11-09). "Cigarette Smoking Among Adults --- United States, 2006". United States Centers for Disease Control and Prevention. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5644a2.htm. Retrieved 2009-01-01. "In 2006, an estimated 20.8% (45.3 million) of U.S. adults[...]" 
  7. ^ a b c d "WHO/WPRO-Smoking Statistics". World Health Organization Regional Office for the Western Pacific. 2002-05-28. http://www.wpro.who.int/media_centre/fact_sheets/fs_20020528.htm. Retrieved 2009-01-01. 
  8. ^ a b c Wingand, Jeffrey S. (July 2006). "ADDITIVES, CIGARETTE DESIGN and TOBACCO PRODUCT REGULATION" (PDF). Mt. Pleasant, MI 48804: Jeffrey Wigand. http://www.jeffreywigand.com/WHOFinal.pdf. Retrieved 2009-02-14. 
  9. ^ a b Gilman & Xun 2004, p. 318
  10. ^ a b Parrott, A. C.; Winder, G. (1989). "Nicotine chewing gum (2 mg, 4 mg) and cigarette smoking: comparative effects upon vigilance and heart rate". Psychopharmacology 97 (2): 257–261. doi:10.1007/BF00442260. PMID 2498936.  edit
  11. ^ a b Parkin, C.; Fairweather, D. B.; Shamsi, Z.; Stanley, N.; Hindmarch, I. (1998). "The effects of cigarette smoking on overnight performance". Psychopharmacology 136 (2): 172–178. doi:10.1007/s002130050553. PMID 9551774.  edit
  12. ^ a b Gilman & Xun 2004, pp. 320–321
  13. ^ a b c Guindon, G. Emmanuel; Boisclair, David (2003) (PDF). Past, current and future trends in tobacco use. Washington DC: The International Bank for Reconstruction and Development / The World Bank. pp. 13–16. http://www1.worldbank.org/tobacco/pdf/Guindon-Past,%20current-%20whole.pdf. Retrieved 2009-03-22 
  14. ^ a b The World Health Organization, and the Institute for Global Tobacco Control, Johns Hopkins School of Public Health (2001). "Women and the Tobacco Epidemic: Challenges for the 21st Century" (PDF). World Health Organization. pp. 5–6. http://www.who.int/tobacco/media/en/WomenMonograph.pdf. Retrieved 2009-01-02. 
  15. ^ a b "Surgeon General's Report—Women and Smoking". Centers for Disease Control and Prevention. 2001. p. 47. http://www.cdc.gov/tobacco/data_statistics/sgr/sgr_2001/sgr_women_chapters.htm. Retrieved 2009-01-03. 
  16. ^ Jordan, Jr., Ervin L.. Jamestown, Virginia, 1607-1907: An Overview. University of Virginia. http://curry.edschool.virginia.edu/socialstudies/projects/jvc/overview.html. Retrieved 2009-02-22 
  17. ^ Kulikoff, Allan (1986-08-01). Tobacco and Slaves: The Development of Southern Cultures in the Chesapeake. The University of North Carolina Press. ISBN 978-0807842249. http://books.google.com/?id=NCvU9_bj-1QC&printsec=frontcover&dq=Tobacco+%26+Slaves:+The+Development+of+Southern+Cultures+in+the+Chesapeake. Retrieved 2009-03-22 
  18. ^ Cooper, William James (October 2000). Liberty and Slavery: Southern Politics to 1860. Univ of South Carolina Press. p. 9. ISBN 978-1570033872. http://books.google.com/?id=AFS3Uu_EMQEC&printsec=frontcover#PPA9,M1. Retrieved 2009-03-22 
  19. ^ Trager, James (August 1994). The People's Chronology: A Year-by-year Record of Human Events from Prehistory to the Present. Holt. ISBN 978-0805031348 
  20. ^ Gilman & Xun 2004, p. 38
  21. ^ Gilman & Xun 2004, pp. 92–99
  22. ^ Gilman & Xun 2004, pp. 15–16
  23. ^ A Counterblaste to Tobacco. University of Texas at Austin. 2002-04-16. http://www.laits.utexas.edu/poltheory/james/blaste/. Retrieved 2009-03-22 
  24. ^ Burns, Eric (2006-09-28). The Smoke of the Gods: A Social History of Tobacco. Temple University Press. pp. 134–135. ISBN 978-1592134809. http://books.google.com/?id=cZfqS7vi9vEC&printsec=frontcover&dq=The+Smoke+of+the+Gods:+A+Social+History+of+Tobacco. Retrieved 2009-03-22 
  25. ^ Proctor 2000, p. 178
  26. ^ Proctor 2000, p. 219
  27. ^ Proctor 2000, p. 187
  28. ^ a b Proctor 2000, p. 245
  29. ^ Proctor, Robert N. (1996). Nazi Medicine and Public Health Policy. Dimensions, Anti-Defamation League. http://www.adl.org/Braun/dim_14_1_nazi_med.asp. Retrieved 2008-06-01 
  30. ^ Doll, R. H. (1 September 1950). "Smoking and Carcinoma of the Lung". British medical journal 2 (4682): 739–748. doi:10.1136/bmj.2.4682.739. ISSN 0007-1447. PMC 2038856. PMID 14772469. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2038856.  edit
  31. ^ Milo Geyelin (November 23, 1998). "Forty-Six States Agree to Accept $206 Billion Tobacco Settlement". Wall Street Journal. 
  32. ^ Hilton, Matthew (2000-05-04). Smoking in British Popular Culture, 1800-2000: Perfect Pleasures. Manchester University Press. pp. 229–241. ISBN 978-0719052576. http://books.google.com/?id=UjM8t6Ul73YC&printsec=frontcover&dq=Smoking+in+British+Popular+Culture#PPA229,M1. Retrieved 2009-03-22 
  33. ^ Gilman & Xun 2004, pp. 46–57
  34. ^ a b MPOWER 2008, pp. 267–288
  35. ^ "Bidi Use Among Urban Youth – Massachusetts, March–April 1999". Centers for Disease Control and Prevention. 1999-09-17. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm4836a2.htm. Retrieved 2009-02-14. 
  36. ^ Pakhale, Ss; Maru, Gb (Dec 1998). "Distribution of major and minor alkaloids in tobacco, mainstream and sidestream smoke of popular Indian smoking products". Food and chemical toxicology 36 (12): 1131–8. doi:10.1016/S0278-6915(98)00071-4. ISSN 0278-6915. PMID 9862656.  edit
  37. ^ Rarick CA (2008-04-02). Note on the premium cigar industry. SSRN. SSRN 1127582. 
  38. ^ Mariolis P, Rock VJ, Asman K et al. (2006). "Tobacco use among adults—United States, 2005". MMWR Morb Mortal Wkly Rep 55 (42): 1145–8. PMID 17065979. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5542a1.htm. 
  39. ^ "A bill to protect the public health by providing the Food and Drug Administration with certain authority to regulate tobacco products. (Summary)" (Press release). Library of Congress. 2004-05-20. http://thomas.loc.gov/cgi-bin/bdquery/z?d108:SN02461:@@@D&summ2=m&. Retrieved 2007-08-01. 
  40. ^ Turner, JA; Sillett, RW; McNicol, MW (1977). "Effect of cigar smoking on carboxyhaemoglobin and plasma nicotine concentrations in primary pipe and cigar smokers and ex-cigarette smokers". British medical journal 2 (6099): 1387–9. doi:10.1136/bmj.2.6099.1387. PMC 1632361. PMID 589225. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1632361.  edit
  41. ^ Armitage, A. K.; Turner (1970). "Absorption of Nicotine in Cigarette and Cigar Smoke through the Oral Mucosa". Nature 226 (5252): 1231–1232. Bibcode 1970Natur.226.1231A. doi:10.1038/2261231a0. PMID 5422597.  edit
  42. ^ Wonnacott, S. (1997). "Presynaptic nicotinic ACh receptors". Trends in Neurosciences 20 (2): 92–34. doi:10.1016/S0166-2236(96)10073-4. PMID 9023878.  edit
  43. ^ Pontieri, F. E.; Tanda, G.; Orzi, F.; Chiara, G. D. (1996). "Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs". Nature 382 (6588): 255–257. Bibcode 1996Natur.382..255P. doi:10.1038/382255a0. PMID 8717040.  edit
  44. ^ Guinan, M. E.; Portas, M. R.; Hill, H. R. (1979). "The candida precipitin test in an immunosuppressed population". Cancer 43 (1): 299–302. doi:10.1002/1097-0142(197901)43:1<299::AID-CNCR2820430143>3.0.CO;2-D. PMID 761168.  edit
  45. ^ Pich, E. M.; Pagliusi, S. R.; Tessari, M.; Talabot-Ayer, D.; Hooft Van Huijsduijnen, R.; Chiamulera, C. (1997). "Common neural substrates for the addictive properties of nicotine and cocaine". Science 275 (5296): 83–86. doi:10.1126/science.275.5296.83. PMID 8974398.  edit
  46. ^ Talhout, R.; Opperhuizen, A.; Van Amsterdam, G. (Oct 2007). "Role of acetaldehyde in tobacco smoke addiction". European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 17 (10): 627–636. doi:10.1016/j.euroneuro.2007.02.013. ISSN 0924-977X. PMID 17382522.  edit
  47. ^ Shoaib, M.; Lowe, A.; Williams, S. (2004). "Imaging localised dynamic changes in the nucleus accumbens following nicotine withdrawal in rats". NeuroImage 22 (2): 847–854. doi:10.1016/j.neuroimage.2004.01.026. PMID 15193614.  edit
  48. ^ Peto, Richard; Lopez, Alan D; Boreham, Jillian; Thun, Michael (2006) (PDF). Mortality from Smoking in Developed Countries 1950-2000: indirect estimates from national vital statistics. Oxford University Press. p. 9. http://www.ctsu.ox.ac.uk/~tobacco/SMK_All_PAGES.pdf. Retrieved 2009-03-22 
  49. ^ Centers for Disease Control and Prevention (CDC) (2009). "Cigarette smoking among adults and trends in smoking cessation - United States, 2008" (Full free text). MMWR. Morbidity and mortality weekly report 58 (44): 1227–1232. PMID 19910909. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5844a2.htm.  edit
  50. ^ GBD 2008, p. 8
  51. ^ GBD 2008, p. 23
  52. ^ a b "WHO/WPRO-Tobacco Fact sheet". World Health Organization Regional Office for the Western Pacific. 2007-05-29. http://www.wpro.who.int/media_centre/fact_sheets/fs_20070529.htm. Retrieved 2009-01-01. 
  53. ^ Gay, Peter (1988). Freud: A Life for Our Time. New York: W. W. Norton & Company. pp. 650–651. ISBN 0393328619. 
  54. ^ Stanton, W. (1992). "A longitudinal study of the influence of parents and friends on children's initiation of smoking". Journal of Applied Developmental Psychology 13 (4): 423–434. doi:10.1016/0193-3973(92)90010-F.  edit
  55. ^ Harris, Judith Rich; Pinker, Steven (1998-09-04). The nurture assumption: why children turn out the way they do. Simon and Schuster. ISBN 978-0684844091. http://books.google.com/?id=9GQlA_l-TQ0C&printsec=frontcover&dq=The+nurture+assumption:+Why+children+turn+out+the+way+they+do. Retrieved 2009-03-22 
  56. ^ Chassin, L.; Presson, C.; Rose, J.; Sherman, S. J.; Prost, J. (2002). "Parental Smoking Cessation and Adolescent Smoking". Journal of Pediatric Psychology 27 (6): 485–496. doi:10.1093/jpepsy/27.6.485. PMID 12177249.  edit
  57. ^ Proescholdbell, R. J.; Chassin, L.; MacKinnon, D. P. (2000). "Home smoking restrictions and adolescent smoking". Nicotine & Tobacco Research 2 (2): 159. doi:10.1080/713688125.  edit
  58. ^ Urberg, K. .; Shyu, S. J.; Liang, J. . (1990). "Peer influence in adolescent cigarette smoking". Addictive Behaviors 15 (3): 247–255. doi:10.1016/0306-4603(90)90067-8. PMID 2378284.  edit
  59. ^ Michell L, West P (1996). Peer pressure to smoke: the meaning depends on the method. 11. pp. 39–49. http://www.oxfordjournals.org/our_journals/healed/online/Volume_11/Issue_01/110039.sgm.abs.html. 
  60. ^ Barber, J.; Bolitho, F.; Bertrand, L. (1999). "The Predictors of Adolescent Smoking". Journal of Social Service Research 26 (1): 51–26. doi:10.1300/J079v26n01_03.  edit
  61. ^ Eysenck, Hans J.; Brody, Stuart (2000-11). Smoking, health and personality. Transaction. ISBN 978-0765806390. http://books.google.com/books?id=&printsec=frontcover&dq=Smoking,+health+and+personality. Retrieved 2009-03-22 
  62. ^ Berlin, I.; Singleton, E. G.; Pedarriosse, A. M.; Lancrenon, S.; Rames, A.; Aubin, H. J.; Niaura, R. (2003). "The Modified Reasons for Smoking Scale: factorial structure, gender effects and relationship with nicotine dependence and smoking cessation in French smokers". Addiction 98 (11): 1575–1583. doi:10.1046/j.1360-0443.2003.00523.x. PMID 14616184.  edit
  63. ^ Nicotine. Imperial College London. http://www.ch.ic.ac.uk/rzepa/mim/drugs/html/nicotine_text.htm. Retrieved 2009-03-22 
  64. ^ Chandra, S.; Chaloupka, F. J. (2003). "Seasonality in cigarette sales: patterns and implications for tobacco control". Tobacco Control 12 (1): 105–107. doi:10.1136/tc.12.1.105. PMC 1759100. PMID 12612375. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1759100.  edit
  65. ^ Chandra, S.; Shiffman, S.; Scharf, M.; Dang, Q.; Shadel, G. (Feb 2007). "Daily smoking patterns, their determinants, and implications for quitting". Experimental and clinical psychopharmacology 15 (1): 67–80. doi:10.1037/1064-1297.15.1.67. ISSN 1064-1297. PMID 17295586.  edit
  66. ^ a b Cigarettes Cost U.S. $7 Per Pack Sold, Study Says
  67. ^ a b Study: Cigarettes cost families, society $41 per pack
  68. ^ a b "Public Finance Balance of Smoking in the Czech Republic". http://www.mindfully.org/Industry/Philip-Morris-Czech-Study.htm. 
  69. ^ "Snuff the Facts". http://www.cato.org/dailys/1-16-98.html. 
  70. ^ Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Mitchell, Richard (2007-05-18). "Chapter 8: Environmental and Nutritional Diseases". Robbins Basic Pathology (8th ed.). Philadelphia: W.B. Saunders. p. 288, Figure 8-6. ISBN 9781416029731. 
  71. ^ Inflamm Bowel Dis. May 2009, P. Seksik, I Nion-Larmurier
  72. ^ WHO global burden of disease report 2008
  73. ^ WHO Report on the Global Tobacco Epidemic, 2008
  74. ^ "Nicotine: A Powerful Addiction." Centers for Disease Control and Prevention.
  75. ^ Cigarette Smoking Among Adults – United States, 2006
  76. ^ WHO/WPRO-Smoking Statistics
  77. ^ Worldwide burden of disease from exposure to second-hand smoke: a retrospective analysis of data from 192 countries 2010-11-26
  78. ^ Mostafa RM. Dilemma of women's passive smoking. Ann Thorac Med [serial online] 2011 [cited 2011 Mar 29];6:55-6. Available from: http://www.thoracicmedicine.org/text.asp?2011/6/2/55/78410
  79. ^ Church of Jesus Christ of Latter-day Saints (2009). "Obey the Word of Wisdom". Basic Beliefs - The Commandments. http://www.mormon.org/mormonorg/eng/basic-beliefs/the-commandments/obey-the-word-of-wisdom. Retrieved 2009-10-15. 
  80. ^ Smith, Peter (2000). "smoking". A concise encyclopedia of the Bahá'í Faith. Oxford: Oneworld Publications. pp. 323. ISBN 1-85168-184-1. 
  81. ^ Updated status of the WHO Framework Convention on Tobacco Control
  82. ^ 26, 2004-smoking-costs_x.htm Study: Cigarettes cost families, society $41 per pack
  83. ^ Reducing Tobacco Use: A Report of The Surgeon General
  84. ^ Higher cigarette prices influence cigarette purchase patterns
  85. ^ http://www.ttb.gov/tax_audit/atftaxes.shtml
  86. ^ State Tax Rates on Cigarettes
  87. ^ Price of cigarettes across the EU
  88. ^ Smuggling & Crossborder Shopping
  89. ^ Scollo, Michelle (2008). "13.2 Tobacco taxes in Australia". Tobacco in Australia. Cancer Council Victoria. Retrieved 2010-07-29.
  90. ^ History of Tobacco Regulation
  91. ^ Television Without Frontiers Directive 1989
  92. ^  European Union - Tobacco advertising ban takes effect July 31 
  93. ^ Report on the implementation of the EU Tobacco Advertising Directive
  94. ^ Tobacco - Health warnings Australian Government Department of Health and Ageing. Retrieved August 29, 2008
  95. ^ Public Health at a Glance - Tobacco Pack Information
  96. ^ Tobacco 18
  97. ^ NFPA:: Press Room:: News releases
  98. ^ Reynolds Letter
  99. ^ a b Fire Safe Cigarettes:: Letter to tobacco companies
  100. ^ C. Merrill, J. .; Kleber, H. D.; Shwartz, M. .; Liu, H. .; Lewis, S. R. (1999). "Cigarettes, alcohol, marijuana, other risk behaviors, and American youth". Drug and Alcohol Dependence 56 (3): 205–212. doi:10.1016/S0376-8716(99)00034-4. PMID 10529022.  edit
  101. ^ Swan, G. C. (1990). "Smoking and alcohol consumption in adult male twins: genetic heritability and shared environmental influences" (Free full text). Journal of substance abuse 2 (1): 39–50. doi:10.1016/S0899-3289(05)80044-6. ISSN 0899-3289. PMID 2136102. http://www.nlm.nih.gov/medlineplus/alcohol.html.  edit

Bibliography

External links